Clinical Informatics

Breaking Digital Health Barriers Through a Large Language Model–Based Tool for Automated Observational Medical Outcomes Partnership Mapping: Development and Validation Study

Meredith CB Adams, Matthew L Perkins, Cody Hudson, Vithal Madhira, Oguz Akbilgic, Da Ma, Robert W Hurley, Umit Topaloglu

J Med Internet Res 2025 (May 15); 27:e69004

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Extracting Multifaceted Characteristics of Patients With Chronic Disease Comorbidity: Framework Development Using Large Language Models

Junyan Zhang, Junchen Zhou, Liqin Zhou, Zhichao Ba

JMIR Med Inform 2025 (May 15); 13:e70096

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A Deep Learning–Enabled Workflow to Estimate Real-World Progression-Free Survival in Patients With Metastatic Breast Cancer: Study Using Deidentified Electronic Health Records

Gowtham Varma, Rohit Kumar Yenukoti, Praveen Kumar M, Bandlamudi Sai Ashrit, K Purushotham, C Subash, Sunil Kumar Ravi, Verghese Kurien, Avinash Aman, Mithun Manoharan, Shashank Jaiswal, Akash Anand, Rakesh Barve, Viswanathan Thiagarajan, Patrick Lenehan, Scott A Soefje, Venky Soundararajan

JMIR Cancer 2025 (May 15); 11:e64697

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Scientific Evidence for Clinical Text Summarization Using Large Language Models: Scoping Review

Lydie Bednarczyk, Daniel Reichenpfader, Christophe Gaudet-Blavignac, Amon Kenna Ette, Jamil Zaghir, Yuanyuan Zheng, Adel Bensahla, Mina Bjelogrlic, Christian Lovis

J Med Internet Res 2025 (May 15); 27:e68998

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Clinical Efficacy and Safety of the Herbal Prescription, HH333, in Preventing Recurrent Stroke in Patients With Ischemic Stroke Induced by Small-Vessel Disease: Protocol for Multicenter, Double-Blind, Randomized, Prospective, Pilot Clinical Trial

Han-Gyul Lee, Seungwon Kwon, Woo-Sang Jung, Sang-Kwan Moon, Cheol-Hyun Kim, Dong-Jun Choi

JMIR Res Protoc 2025 (May 13); 14:e70953

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Pragmatic Risk Stratification Method to Identify Emergency Department Presentations for Alternative Care Service Pathways: Registry-Based Retrospective Study Over 5 Years

John Rong Hao Tay, Yohei Okada, Gayathri Devi Nadarajan, Fahad Javaid Siddiqui, Tomás Barry, Marcus Eng Hock Ong

J Med Internet Res 2025 (May 12); 27:e73758

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Evaluation and Bias Analysis of Large Language Models in Generating Synthetic Electronic Health Records: Comparative Study

Ruochen Huang, Honghan Wu, Yuhan Yuan, Yifan Xu, Hao Qian, Changwei Zhang, Xin Wei, Shan Lu, Xin Zhang, Jingbao Kan, Cheng Wan, Yun Liu

J Med Internet Res 2025 (May 12); 27:e65317

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Effects of the National Institutes of Health Stroke Scale and Modified Rankin Scale on Predictive Models of 30-Day Nonelective Readmission and Mortality After Ischemic Stroke: Cohort Study

Mai N Nguyen-Huynh, Janet Alexander, Zheng Zhu, Melissa Meighan, Gabriel Escobar

JMIR Med Inform 2025 (May 09); 13:e69102

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Assessing the Impact on Electronic Health Record Burden After Five Years of Physician Engagement in a Canadian Mental Health Organization: Mixed-Methods Study

Tania Tajirian, Brian Lo, Gillian Strudwick, Adam Tasca, Emily Kendell, Brittany Poynter, Sanjeev Kumar, Po-Yen (Brian) Chang, Candice Kung, Debbie Schachter, Gwyneth Zai, Michael Kiang, Tamara Hoppe, Sara Ling, Uzma Haider, Kavini Rabel, Noelle Coombe, Damian Jankowicz, Sanjeev Sockalingam

JMIR Hum Factors 2025 (May 09); 12:e65656

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2024: A Year of Nursing Informatics Research in Review

Elizabeth Borycki

JMIR Nursing 2025 (May 07); 8:e74345

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Optimizing Clinical Decision Support System Functionality by Leveraging Specific Human-Computer Interaction Elements: Insights From a Systematic Review

Ali Azadi, Francisco José García-Peñalvo

JMIR Hum Factors 2025 (May 06); 12:e69333

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Code Error in “Diagnostic Classification and Prognostic Prediction Using Common Genetic Variants in Autism Spectrum Disorder: Genotype-Based Deep Learning”

Catriona Miller, Theo Portlock, Denis M Nyaga, Greg D Gamble, Justin M O'Sullivan

JMIR Med Inform 2025 (May 06); 13:e66556

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Process Re-Engineering and Data Integration Using Fast Healthcare Interoperability Resources for the Multidisciplinary Treatment of Lung Cancer

Ching-Hsiung Lin, Bing-Yen Wang, Sheng-Hao Lin, Pei Hsuan Shih, Chin-Jing Lee, Yung Ting Huang, Shih Chieh Chen, Mei-Lien Pan

JMIR Cancer 2025 (May 05); 11:e53887

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Electronic Implementation of Patient-Reported Outcome Measures in Primary Health Care: Mixed Methods Systematic Review

Maxime Sasseville, Wilfried Supper, Jean-Baptiste Gartner, Géraldine Layani, Samira Amil, Peter Sheffield, Marie-Pierre Gagnon, Catherine Hudon, Sylvie Lambert, Eugène Attisso, Steven Ouellet, Mylaine Breton, Marie-Eve Poitras, Pierre-Henri Roux-Lévy, James Plaisimond, Frédéric Bergeron, Rachelle Ashcroft, Sabrina T. Wong, Antoine Groulx, Jean-Sébastien Paquette, Natasha D'Anjou, Sylviane Langlois, Annie LeBlanc

J Med Internet Res 2025 (May 05); 27:e63639

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Developing a Scalable Annotation Method for Large Datasets That Enhances Alarms With Actionability Data to Increase Informativeness: Mixed Methods Approach

Sophie Anne Inès Klopfenstein, Anne Rike Flint, Patrick Heeren, Mona Prendke, Amin Chaoui, Thomas Ocker, Jonas Chromik, Bert Arnrich, Felix Balzer, Akira-Sebastian Poncette

J Med Internet Res 2025 (May 05); 27:e65961

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The Impact of Online Labor Platforms on Workforce Management in Health Care

Maryam Ahmadi Shad, Michael Simon, Florian Liberatore

Interact J Med Res 2025 (May 02); 14:e68546

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Development of a Predictive Model for Metabolic Syndrome Using Noninvasive Data and its Cardiovascular Disease Risk Assessments: Multicohort Validation Study

Jin-Hyun Park, Inyong Jeong, Gang-Jee Ko, Seogsong Jeong, Hwamin Lee

J Med Internet Res 2025 (May 02); 27:e67525

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Toward Real-Time Discharge Volume Predictions in Multisite Health Care Systems: Longitudinal Observational Study

Fernando Acosta-Perez, Justin Boutilier, Gabriel Zayas-Caban, Sabrina Adelaine, Frank Liao, Brian Patterson

J Med Internet Res 2025 (Apr 30); 27:e63765

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Enhancing Interoperability for a Sustainable, Patient-Centric Health Care Value Chain: Systematic Review for Taxonomy Development

Carlos Antonio Marino, Claudia Diaz Paz

J Med Internet Res 2025 (Apr 25); 27:e69465

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Enhancing Bidirectional Encoder Representations From Transformers (BERT) With Frame Semantics to Extract Clinically Relevant Information From German Mammography Reports: Algorithm Development and Validation

Daniel Reichenpfader, Jonas Knupp, Sandro Urs von Däniken, Roberto Gaio, Fabio Dennstädt, Grazia Maria Cereghetti, André Sander, Hans Hiltbrunner, Knud Nairz, Kerstin Denecke

J Med Internet Res 2025 (Apr 25); 27:e68427

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